Gross and histopathological lesions in the skin of
respectively 10 and 8 cows affected with systemic granulomatous
disease associated with pasturing vetch (Vicia spp.) are described.
In all cases, the cutaneous lesions were characterized by multiple
coalescent areas of alopecia, lichenification and desquamation.
More frequently affected sites were the skin covering the head
and neck (10/10), trunk (4/10), escutcheon (3/10) and mammary
gland (2/10). In all 8 histologically examined cases the lesions
were characterized by superficial perivascular granulomatous
dermatitis of varying intensity. Other histological findings
included deep perivascular dermatitis (1/8), perifoliculitis (2/8),
mural foliculitis (3/8), compact orthokeratotic hyperkeratosis (6/
8), erosions (1/8), ulcers (2/8), Munros microabscess (8/8),
serocellular crusts (1/8), spongiosis (4/8), hydropic degeneration
(5/8), acantholysis (1/8), Civatte bodies (2/8), lymphoplasmacytic
exocytosis (6/8), superficial edema (6/8), pigmentary incontinence
(2/8), basophilia (6/8) and collagen dystrophic mineralization
(2/8), swollen nucleus of endothelial cells (8/8) and sweat gland
Keywords: diseases of cattle, vetch poisoning, Vicia spp.
poisoning, granulomatous dermatitis,