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Methyl parathion (MP) is a commonly used organophosphorus insecticide, commercially available as Folidol 600. This chemical substance was tested to determine micronucleus (MN) frequencies in peripheral erythrocytes of the fish Cypnnus c e i o treated in vivo. The concentrations tested were 1.25,2.50,5.00 and 7.50 ppm. Fish were killed after 24 or 48 h of treatment. There was a significant increase in the frequency of micronuclei in the animals treated with 2.50 and 5.00 ppm after 24 h. At higher dosages this effect disap peared probably due to the increased cell lethality. The frequency of MN induction was lower at 48 than at 24 h after treatment. There was a dosedependent increase in MN frequency which, however, was significant only at the highest concentration (7.50 ppm) compared to control.

Palabras clave: Cypinus c a p , micronucleus test, methyl parathion.
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Universidad Autónoma del Estado de México
Sistema de Información Científica Redalyc ®
Versión 3.0 | 2017
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