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Protective effect of Spirulina platensis on fatty liver induced by a single sublethal dose of carbon tetrachloride in wistar rats
Patricia Victoria TORRES-DURÁN, Aldo FERREIRA-HERMOSILLO, Arnulfo RAMOS-JIMÉNEZ, Rosa Patricia HERNÁNDEZ-TORRES, María Cristina PAREDES-CARBAJAL, Marco Antonio JUÁREZ-OROPEZA;
Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas 2014 13(2)
Resumen
Inglés Español
It has been reported that Spirulina maxima and other natural products are effective in attenuating hepatic damage. In this study were analyzed the effects of five days dietary Spirulina platensis (5%) in rats with fatty liver induced by CCl4 (2 mL/kg b.w.). Animals were sacrificed at 24 and 48 h post-treatment. In the liver were evaluated total lipids by gravimetry and lipid profile by enzymatic-colorimetric methods, the concentration of thiobarbituric acid reactive substances and nitric oxide by chemical methods. In serum, alanine aminotransferase (kinetic method) and lipid profile were evaluated. The most important effects on the liver were: attenuation in lipid peroxidation, minimal variations on the total fatty acid methyl esters profile, and nitric oxide. These results suggest that Spirulina platensis could be used for fatty liver treatment as an alimentary supplement.

Palabras clave: TBARS, antioxidants, triacylglycerols, nitric oxide, cyanobateria, lipids.
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Universidad Autónoma del Estado de México
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Versión 3.0 | 2017
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